Poly(2-hydroxyethyl methacrylate)

Description	Solid Poly(2-hydroxyethyl methacrylate) (pHEMA) is brittle, while pHEMA hydrogel is a soft material. Glass transition temperature for pHEMA hydrogels is reduced by increasing a content of water in the matrix. Macromolecular properties in pHEMA are characterized by non-covalent interactions of hydrogen-bonds among the polymer chains as well as the hydrated water molecules. The presence of polar groups of hydroxyl and carboxyl on each repeat unit makes this polymer compatible with water. The hydrophobic a-methyl groups of the backbone convey hydrolytic stability to the polymer and enhance mechanical strength of the polymer matrix.
IUPAC Name	2-hydroxyethyl 2-methylprop-2-enoate
Molecular Weight	130.14g/mol
Molecular Formula	(C6H10O3)n
Canonical SMILES	CC(=C)C(=O)OCCO
InChI	1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
InChI Key	WOBHKFSMXKNTIM-UHFFFAOYSA-N
Boiling Point	67 °C @ 3.5 mm Hg;250 °C (calculated)
Melting Point	FP: -12 °C
Flash Point	97 °C (closed cup);97 °C c.c.
Density	1.034 @ 25 °C/4 °C;1.07 g/cm³
Solubility	0.77 M;Miscible with water and soluble in common org solvents;Solubility in water: miscible
Application	pHEMA scaffolds are used in tissue engineering. It can be used in hydrogels for biomedical applications, as sorbents for metal ions.pHEMA has been used in applications such as soft contact lenses, in drug delivery systems, and in kidney dialysis membranes.Nanoparticles of pHEMA may be employed as a carrier for controlled delivery of anticancer and antitumor drugs.
Storage	room temp
EC Number	212-782-2;927-388-2
Form	crystals
MDL Number	MFCD00084374
Packaging	1, 10 g in glass bottle
Quality Level	200
Refractive Index	Index of refraction: 1.4515 @ 20 °C/D
Transition Temperature	Tg 84.8 °C
Vapor Pressure	0.13 mmHg;0.126 mm Hg @ 25 °C;Vapor pressure, Pa at 25 °C: 17
Viscosity	8.4 mm2/s at 20 °C